Hallucinating schizophrenia patients have longer left arcuate fasciculus fiber tracks: a DTI tractography study
نویسندگان
چکیده
منابع مشابه
Integrity of the arcuate fasciculus in patients with schizophrenia with auditory verbal hallucinations: A DTI-tractography study
Auditory verbal hallucinations (AVH) of schizophrenia are associated with a disrupted connectivity between frontal and temporoparietal language areas. We hypothesized that this dysconnectivity is underpinned by white matter abnormalities in the left arcuate fasciculus, the main fiber bundle connecting speech production and perception areas. We therefore investigated the relationship between AVH...
متن کاملWhite matter tracts in first-episode psychosis: A DTI tractography study of the uncinate fasciculus
A model of disconnectivity involving abnormalities in the cortex and connecting white matter pathways may explain the symptoms and cognitive abnormalities of schizophrenia. Recently, diffusion imaging tractography has made it possible to study white matter pathways in detail, and we present here a study of patients with first-episode psychosis using this technique. We studied the uncinate fasci...
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L. Serra, M. Cercignani, R. Perri, B. Spanò, L. Fadda, C. Marra, F. Giubilei, C. Caltagirone, and M. Bozzali Neuroimaging laboratory, Fondazione IRCCS Santa Lucia, Roma, Italy, Department of Clinical and Behavioural Neurology, Fondazione IRCCS Santa Lucia, Roma, Italy, Department of Neuroscience, University of Rome ‘Tor Vergata’, Rome, Italy, Institute of Neurology, Università Cattolica, Roma, ...
متن کاملLeftward asymmetry in relative fiber density of the arcuate fasciculus.
Left hemispheric language dominance is well established, but the structural substrate for this functional asymmetry is uncertain. We report a strong asymmetry in the relative fiber density of the arcuate fasciculus, a white matter pathway associated with language that connects the frontal, temporal, and parietal lobes. Measured with diffusion tensor tractography, nearly all study participants d...
متن کاملReduced integrity of the left arcuate fasciculus is specifically associated with auditory verbal hallucinations in schizophrenia
BACKGROUND Schizophrenia patients with auditory verbal hallucinations (AVH) have reduced structural integrity in the left arcuate fasciculus (AFL) compared to healthy controls. However, it is neither known whether these changes are specific to AVH, as opposed to hallucinations or schizophrenia per se, nor how radial and/or axial diffusivity are altered. This study aimed to test the hypothesis t...
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ژورنال
عنوان ژورنال: Psychiatry Research: Neuroimaging
سال: 2020
ISSN: 0925-4927
DOI: 10.1016/j.pscychresns.2020.111088